Biotransformation Specialist for Radioligand Therapeutics (RLTs)

Your main accountabilities will include:

• Design and execution of biotransformation studies to assess RLT metabolic pathways and structural elucidation of metabolites
• Organize and prepare experimental protocols and study reports with upload of results to a centralized database
• Presentation of key findings to project teams and/or other stakeholders
• Monitoring data collection during clinical trials, ensuring adherence to study protocols and regulatory requirements. The role also involves providing valuable insights for experimental study design, contributing to the development of lab manuals, study protocols, and reports. Furthermore, reviewing and interpreting of reported data for accuracy and completeness.
• Coordination and monitoring of clinical RLT studies run under GCP
• Assure quality standard guidelines and safe work practices are applied while working in the laboratories

Minimum Requirements

• Degree in organic/analytical/biochemistry with Biotransformation experience in an industry setting
• A very good understanding of handling of radioisotopes is essential for this role
• Experience in monitoring of clinical trials would be desirable
• Title and salary will be commensurate with experience

The ideal candidate will draw from any the following key skillsets:

• Excellent (hands-on) experience with UPLC, mass spectrometry, especially high-resolution mass spectrometry and ICP-MS
• Extensive hands-on experience with radiometabolite assessment and radiodetection techniques
• Good understanding of in vitro and in vivo drug metabolism of peptides and small molecules
• Good attention to detail, an analytical investigative and questioning nature, with an innovative solution-oriented approach
• A sharp and objective intellect, experienced in balancing big picture thinking with an investigative nature, drilling into detail as appropriate
• Well-developed interpersonal skills with good presence, experienced presenter, and excellent communication skills
• A self-starter and decision maker with an open, confident and persuasive manner who succeeds through influence
• Good planning, prioritization, problem solving and organizational skills
• Resilient, energetic and enthusiastic with the ability to respond constructively to challenging new ideas and feedback
• Team player, ability to be flexible and adapt to a changing environment.
• Good IT skills particularly Word, Excel and PowerPoint